ABSTRACT: Atheroma is a chronic disease of the arterial tree which evolution leads to severe and potentially lethal ischemic events in different organs (brain, heart, disgestive tract, kidneys and limbs). For complex and largely ignored reasons the retention of lipid particles in the subendothelial space of arteries initiates a local humoral and cellular response which progressively leads to a plaque formation by recruitment of systemic macrophages and multiplication of smooth muscle cells of the artery. This plaque formation is followed by expansion/rupture/calcification and eventually causes thrombosis of the vessel. Diet connection with health was first formulated by Hippocrates (360 BC), connection with atheroma suspected by Keys (1904-2004) and later by Ornish in 1990… They popularised Mediterranean diet and vegan style diet but the recognition of diet as a major part of treatment of atheroma occurred still later. Now it is largely admitted in the literature that atheroma is diet dependent but also paradoxically that it’s a "natural" phenomenon in the arterial tree especially with aging. Paleo diet is a rather new topic in medicine although Boyd Eaton described the hypothesis of an evolutionary discordance between industrial diet and our genomics in the NEJM in 1989! Since numerous studies increased our knowledge and shed a very transparent light on what ate our ancestors. Aside the fact that they ate raw fruits, vegetables, meat and fish, the nutrients of these <b>…</b>
New Answers to High Cholesterol